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Access this article Similar content being viewed by others Data availability Gene expression RNAseq (HTseq) and somatic mutation profiles were downloaded from The Cancer Genome Atlas database (TCGA: Phenotype and survival data were downloaded from the University of California SANTA CRUZ (UCSC: GEO datasets are all downloadable from the National Center for Biotechnology Information (NCBI) online Gene Expression Omnibus (GEO) database ( Human mitochondrial-related genes were retrieved from Gene Set Enrichment Analysis ( Pathway-related genes were downloaded from GSEA ( Gene lists encoding immunomodulators and chemokines were downloaded from translation initiation site database (TISDB) website ( The same sample of gene expression and drug sensitivity data was downloaded from the cellminer website ( References Ameri K, Jahangiri A, Rajah AM, Tormos KV, Nagarajan R, Pekmezci M et al (2015) HIGD1A regulates oxygen consumption, ROS production, and AMPK activity during glucose deprivation to modulate cell survival and tumor growth

Short answer: Its unlikely that vaping is thesole cause of bloating in most people, but yesit maycontribute significantly to bloating or digestive discomfort in some users, especially if other factors are present